Blue, crafted through indigo DNA and fermentation.

Better Bluefor Everyday Denim

The blue that touches your skin throughout life has been reborn through synthetic biology. For skin health, Blugene is an indigo that never compromises—even on the smallest risks.

Better Blue for Everyday Denim

A caregiver in a denim jacket holds a child while looking out over cornfields, meadows and water. This is the brand image used on the cover of the supplied catalogue.

Brand image · Image included on p.1 of the catalog

98%
Biobased carbon content
Not detected
Aniline
Not detected
N-methylaniline

These are test results from the supplied catalogue. Not detected means below the method detection limit of 5 mg/kg under the stated test method; it does not mean a content of 0. The 98% figure is biobased carbon content, not indigo purity or an emissions reduction rate.

  • Source: catalogue p.3 Table 1-1 (KATRI, ASTM D6866-24a Method B)
  • Source: catalogue p.5 Table 2-3 (KOTERI, KS K 0734 2019)
See the detailed test data

PRODUCT FORMS

Two forms: powder and printing ink.

Indigo made by microbial fermentation is supplied as a powder for fabric dyeing and as an ink for digital printing.

Deep blue bio indigo powder in a dish (catalogue p.9)

Blugene Indigo Powder

Catalogue p.8

Cotton, silk, and cashmere dyeing evaluation data are included in the catalog.

CAS
482-89-3

The product names above are the web-facing names of the new brand. In the catalogue and the certificates the original product name is “Bio Indigo Dye Powder (Microbial Fermentation) / CB Bio Indigo Dye Powder”.

A glass bottle of deep blue bio indigo digital printing ink (catalogue p.9)

Blugene Digital Printing Ink

Catalogue p.9

A bio indigo ink for digital printing. We are glad to discuss applications and samples with you.

The product names above are the web-facing names of the new brand. In the catalogue and the certificates the original product name is “BioIndigo Digital Printing Ink”.

Particle size, viscosity, shelf life, minimum order quantity, production capacity and pricing are not in the supplied material and are therefore not shown. Please contact us and we will confirm the specifications you need.

Color development by number of dyeing cycles

Test photograph

A three-row, four-column comparison plate. The rows are chemical indigo powder, bio indigo powder and bio indigo digital printing ink; the columns are 1 to 4 dyeing cycles.

For this example the catalogue records color strength as “digital printing ink > chemical indigo ≈ bio indigo powder”. The shade depth in the photograph has not been converted into K/S values or ΔE color difference measurements, and it does not imply superior performance under all conditions.

Request product information

A three-row, four-column comparison plate. The rows are chemical indigo powder, bio indigo powder and bio indigo digital printing ink; the columns are 1 to 4 dyeing cycles.

Photographs from the supplied catalogue, resized for the web without any color correction.

Catalogue p.8 Figure 5-1. A comparison of cotton fabric dyed 1 to 4 times with chemical indigo (powder), bio indigo (powder) and bio indigo (digital printing ink).

ACROSS BORDERS. ACROSS GENERATIONS.

Because it touches our skin for a lifetime.

No matter the country or age, denim is part of our daily life. Because it is worn for years and touches the skin every day, we re-examined every step, from making the color and dyeing to the moment the denim is worn, together with dermatologists, the specialists in skin health. Blugene began with the following three questions.

  • What is it made from
  • What impurities remain
  • Can the results be verified

WHAT REMAINS MATTERS

Our standards reach beyond what you can see.

In the tests presented in the catalog, CutisBio bio indigo, the foundation of Blugene, showed that aniline and N-methylaniline were not detected.

Aniline and N-methylaniline are used as starting materials or intermediates in chemical synthesis routes, and they can remain as unreacted residues in the final indigo powder. A number of certification standards limit the permitted concentration of these substances in textile dyes and in finished products.

Aniline (mg/kg)
Not detectedN.D.
N-methylaniline (mg/kg)
Not detectedN.D.
Method detection limit
5 mg/kg
Test method
KS K 0734 2019
Testing institute
KOTERI (Korea High Tech Textile Research Institute)
Test report number
2025-0604-1132-C03(Test report date 2025-06-10)

Not detected (N.D.) means below the method detection limit under the stated test method. It is not a measured value of 0, and it is not shown as a zero bar in the charts.

Aniline and N-methylaniline analysis of commercial indigo dyes

  • Aniline (mg/kg)
  • N-methylaniline (mg/kg)
  • N.D.Not detected
Aniline and N-methylaniline analysis of commercial indigo dyesAniline and N-methylaniline comparison (mg/kg) · Every value in the charts can also be found in the tables below. Not detected (N.D.) means below the method detection limit under the stated test method. It is not a measured value of 0, and it is not shown as a zero bar in the charts.07501,5002,2503,000Aniline and N-methylaniline comparison (mg/kg)1,524828Company S369225Company M1,2291,127Company ZN.D.N.D.Company M13185Company XTCompanyXTN.D.N.D.Company IN.D.N.D.Company XBCompanyXB2,6522,375Company HN.D.N.D.CutisBioChemicalPlantBio

The nine commercial samples from catalogue p.5 Figure 2-2 and Table 2-3. The vertical axis is in mg/kg and starts at 0.

Every value in the charts can also be found in the tables below.

Aniline and N-methylaniline analysis of commercial indigo dyes
SampleIndigo typeAniline (mg/kg)N-methylaniline (mg/kg)
Company SChemical1,524828
Company MChemical369225
Company ZChemical1,2291,127
Company MPlantNot detectedNot detected
Company XTPlant13185
Company IPlantNot detectedNot detected
Company XBPlantNot detectedNot detected
Company HPlant2,6522,375
CutisBioBioNot detectedNot detected

Not detected (N.D.) means below the method detection limit under the stated test method. It is not a measured value of 0, and it is not shown as a zero bar in the charts.

Company names follow the anonymized labels used in the catalogue. We do not speculate about the actual company names.

Company M appears under both chemical indigo and plant indigo. It is labelled with its type so the two can be told apart.

These values are a comparison of the nine samples included in the catalogue and are not statistics representing the market as a whole. The carbon test and the aniline test differ in institute, method and date, so they have not been combined into a single indicator.

Source · Catalogue p.5 Table 2-3 · Figure 2-2 · Data as of 2026-09-06

Test photographCatalogue p.5 Figure 2-2

Aniline and N-methylaniline analysis of commercial indigo dyes

Photographs from the supplied catalogue, resized for the web without any color correction.

Photographs from the supplied catalogue, resized for the web without any color correction.

SYNTHETIC BIOLOGY

Rewriting the DNA of indigo.

CutisBio produces indigo by utilizing microorganisms' biosynthetic pathways and fermentation.

From feedstock to fabric

Concept image
  1. Photo of a cornfield. This is a conceptual image representing biomass raw materials and is not a photograph of CutisBio's farm.

    Renewable feedstock

    Renewable carbon from biomass such as corn is the starting point.

  2. Photograph of fermentation equipment. Two workers stand in front of control panels, with fermenters showing blue culture solution through inspection windows. This is a conceptual image representing the fermentation process and not a photo of CutisBio facilities or employees.

    Microbial fermentation

    Indigo is made by fermentation that draws on the biosynthetic pathways of microorganisms.

  3. Photo of a glass jar containing blue indigo powder and a bottle of digital printing ink. This is a conceptual image representing two product forms and is not a photograph of CutisBio's products.

    Indigo recovery and product forms

    After recovery and purification, it is made into powder and digital printing ink.

  4. Photograph of a dyeing factory where blue bundles of yarn pass over rollers on an indigo dye vat. This is a conceptual image representing fabric dyeing and not a photo of CutisBio facilities.

    Fabric dyeing and printing

    It is applied to cotton, silk and cashmere dyeing and to digital printing.

Blugene's journey into denim begins with renewable plant feedstock: the blue DNA of indigo is reborn as dye and ink through synthetic biology and precision fermentation. The resulting Blugene indigo dye holds certifications such as ZDHC MRSL, OEKO-TEX ECO PASSPORT and USDA BioPreferred, and it is the dye that colors the denim we wear.

Explore the technology

FROM RENEWABLE CARBON

Thinking of the wearer. And of how it is made.

An indigo that starts from renewable carbon. From the origin of the feedstock through to compositional analysis, we explain our approach with material you can verify.

98%

Biobased carbon content

This is the share of the carbon in the product that comes from renewable feedstock. It is based on the measured value in catalogue p.3 Table 1-1 (pMC 97.73), and it is not indigo purity or a carbon emissions reduction rate.

Product-level life cycle assessment (LCA), water use, energy and carbon emissions data are not included in this catalogue. Environmental performance figures outside the verified scope are not shown on this site.

See the supporting material
A conceptual value-chain image running from feedstock crops through fermentation equipment and blue fabric to a person wearing denim. These are not photographs of an actual CutisBio plant or staff.
Concept image

This image is used to illustrate a concept; it is not a photograph of an actual facility, customer or test result. Catalogue p.12

PERFORMANCE

Dyeability confirmed on real fabric.

Cotton, silk and cashmere were dyed with plant, chemical and bio indigo and compared. The catalogue records comparable performance in colorfastness to laundering, light, rubbing and perspiration.

Test photograph

Photograph of nine fabric swatches. From the left: cotton, silk and cashmere dyed with plant indigo (#1–#3), then chemical indigo (#4–#6), then bio indigo (#7–#9).

Photographs from the supplied catalogue, resized for the web without any color correction.

Catalog p.6 Figure 3-1.
  • Plant indigo

    • #1Cotton
    • #2Silk
    • #3Cashmere
  • Chemical indigo

    • #4Cotton
    • #5Silk
    • #6Cashmere
  • Bio indigo

    • #7Cotton
    • #8Silk
    • #9Cashmere
Test photograph

Photograph of nine fabric swatches. From the left: cotton, silk and cashmere dyed with plant indigo (#1–#3), then chemical indigo (#4–#6), then bio indigo (#7–#9).

Photographs from the supplied catalogue, resized for the web without any color correction.

Photographs from the supplied catalogue, resized for the web without any color correction.

This does not mean superiority in every category. Lower grades are also recorded for some colorfastness to rubbing items, and they appear in the tables exactly as recorded.

See the full colorfastness tables

SHADE LIBRARY

Your brand. Your blue.

Shade depth changes with dye concentration and the number of dyeing cycles. Adjusting the ratio of indigo to indirubin makes it possible to create a shade that belongs to your brand alone.

Catalogue swatches by concentration

The catalogue does not give concentration values for the individual swatches, so they are identified by position (A1–B6).

Catalogue figure
Row A
Dyed swatch A1 by concentration from catalogue p.7 Figure 4-1
A1
Dyed swatch A2 by concentration from catalogue p.7 Figure 4-1
A2
Dyed swatch A3 by concentration from catalogue p.7 Figure 4-1
A3
Dyed swatch A4 by concentration from catalogue p.7 Figure 4-1
A4
Dyed swatch A5 by concentration from catalogue p.7 Figure 4-1
A5
Dyed swatch A6 by concentration from catalogue p.7 Figure 4-1
A6
Row B
Dyed swatch B1 by concentration from catalogue p.7 Figure 4-1
B1
Dyed swatch B2 by concentration from catalogue p.7 Figure 4-1
B2
Dyed swatch B3 by concentration from catalogue p.7 Figure 4-1
B3
Dyed swatch B4 by concentration from catalogue p.7 Figure 4-1
B4
Dyed swatch B5 by concentration from catalogue p.7 Figure 4-1
B5
Dyed swatch B6 by concentration from catalogue p.7 Figure 4-1
B6
LowHigh

Blugene concentration

How indirubin shifts the shade

Indirubin is the red isomer of indigo. Adjusting the composition of indigo and indirubin produced by microbial fermentation makes it possible to create a blue that is unique to your brand.

Photograph of denim fabric dyed with 100% indigo (catalogue p.7 Figure 4-2)

Photographs from the supplied catalogue, resized for the web without any color correction.

Indigo 100%

Photograph of denim fabric dyed with 94% indigo and 6% indirubin (catalogue p.7 Figure 4-2)

Photographs from the supplied catalogue, resized for the web without any color correction.

Indigo 94%, indirubin 6%

These are photographs of the two compositions presented in the catalogue. Mixing ratios in between are not provided, so we do not generate those colors on screen.

Actual color may differ depending on the screen, the fabric and the dyeing conditions. Please confirm with a fabric sample.

The pharmacological activity of indirubin is not covered on this site. We describe it only from the perspective of shade control and product development.

DATA & CERTIFICATIONS

Trust you can check against the source.

Test results and certificates are gathered in one place. Each item is shown with its testing institute, test method, report number and data as-of date, and the original can be viewed.

  • ZDHC MRSL Level 1 Version 3.1 certification mark

    ZDHC MRSL Level 1 Version 3.1

    Original image of the ZDHC MRSL Level 1 Version 3.1 certificate

    Press Esc to close.

  • OEKO-TEX® ECO PASSPORT certification mark

    OEKO-TEX® ECO PASSPORT

    Original image of the OEKO-TEX® ECO PASSPORT certificate

    Press Esc to close.

  • USDA BioPreferred® certification mark

    USDA BioPreferred®

    Original image of the USDA BioPreferred® certificate

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  • TÜV AUSTRIA OK biobased — Class 5 certification mark

    TÜV AUSTRIA OK biobased — Class 5

    Original image of the TÜV AUSTRIA OK biobased — Class 5 certificate

    Press Esc to close.

The original catalogue

Let's create your next blue.

We welcome inquiries from denim brands, fabric mills, dye houses, and printing companies.

contact@cutisbio.com+82-70-4914-2525